First up, here are some things you can expect:  

• a new artifact Food

• “mind swap” as flavor words

• a new card with “Rocket-Powered” in its name

• some new counters – ingenuity and film

• a five-color Spider-Man

• a reanimation spell that can reanimate a number of creatures never used before

• a card that keeps the “legend rule” from applying to Spiders

• a card that lets you exchange life with another player

• a character, other than Miles, from the Ultimate universe

• a famous Spider-Man meme is made into a card

Next, here are some rules text that will be showing up on cards:  

• “Exile those tokens when Mysterio leaves the battlefield.”

• “choose a card type other than creature.”

• “Look at the top nine cards of target opponent’s library,”

• “You may cast this card from your graveyard by discarding a card in addition to paying its other costs.”

• “Whenever a creature you control with menace attacks, create a Treasure token.”

• “You don’t lose unspent red mana as steps and phases end.”

• “If you do, draw X cards, then you may put a permanent card with mana value X or less from your hand onto the battlefield.”

• “loses all abilities and becomes a green Lizard”

• “Until next turn, he becomes a land and gains “T: Add {U}.”

• “Whenever you attack with two or more Spiders,”